Simultaneous Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Pharmaceutical Dosage Form by RP-HPLC
نویسندگان
چکیده
منابع مشابه
Development and validation of a stability indicating RP-HPLC method for simultaneous estimation of Olmesartan Medoxomil and Metoprolol Succinate in pharmaceutical dosage form
AIM AND BACKGROUND A simple, rapid, precise and isocratic RP-HPLC (Reverse Phase High Performance Liquid Chromatography) method is aimed to develop for the simultaneous estimation of Olmesartan Medoxomil and Metoprolol Succinate in bulk drug and pharmaceutical dosage form. MATERIALS AND METHODS The quantification is carried out using YMC-Pack CN (250 × 4.6 mm, 5.0 μm) column and the mobile ph...
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A new, simple, precise, accurate and sensitive UV ‐ Spectrophotometric absorption correction method has been developed for simultaneous determination of Metoprolol Succinate and Olmesartan Medoxomil in combined tablet dosage form. Methanol was used as solvent. Absorbance correction method was based on the property of additivity of absorbances. The two wavelengths on Olmesartan medoxomil curve w...
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A simple, precise, specific and accurate reverse phase HPLC method has been developed for the simultaneous determination of Metoprolol succinate (METO) and Olmesartan medoxomil (OLME) in tablet dosage form. The chromatographic separation was achieved on inertsil ODS 3V (250 mm×4.6 mm, 5 μm) column using PDA detector. The mobile phase consisting of Buffer (2 ml O-phosphoric acid in 2000 ml milli...
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A simple, precise and rapid RP-HPLC method was developed for the simultaneous determination of simvastatin and ezetimibe in combined pharmaceutical dosage forms. The method was carried out on a Shim-pack, RP-C18 column using a mixture of acetonitrile: methanol: buffer (triethylamine pH-3) in the ratio 15:45:40 and detection was done at 240 nm using external standard method as quantitation. The ...
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ژورنال
عنوان ژورنال: Journal of Chromatography & Separation Techniques
سال: 2012
ISSN: 2157-7064
DOI: 10.4172/2157-7064.1000151